DOUBLE-STRANDED DNA IN EXOSOMES OF MALIGNANT PLEURAL EFFUSIONS AS A NOVEL DNA SOURCE FOR EGFR MUTATION DETECTION IN LUNG ADENOCARCINOMA

Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma

Background: Exosomes are cell-derived vesicles and bear a specific set of nucleic acids including DNA (exoDNA).Thus, this study is to explore whether exoDNA in malignant pleural effusions (MPEs) could be a novel DNA source for mutation detection of epidermal growth factor receptor (EGFR).Methods: In this study, 52 lung adenocarcinoma patients were

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Quantifying agreement between anatomical and functional interhemispheric correspondences in the resting brain.

The human brain is composed of two broadly symmetric cerebral hemispheres, with an abundance of reciprocal anatomical connections between homotopic locations.However, to date, studies of hemispheric symmetries have not identified correspondency precisely due to variable cortical folding patterns.Here Perfume we present a method to establish accurat

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Geschichte der Natur bei Alexander von Humboldt

Article in German, Abstracts in English, German and French.This article analyses the importance of an historical view of nature in the works of Alexander von Humboldt.In several of his first writings, Humboldt seems to outline the importance of what one may call history of nature.But even before his famous American travel, his Perfume position chan

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